Mouth spray

Why we chose this dosage form

Dietary supplements are not just about ingredients – they are also about how they are used. The form of administration can influence how well a product integrates into daily life. In the scientific literature, this relationship is described under the term "adherence" – that is, how consistently a product is used over a longer period of time.^{^1,2}

Studies show that the simpler an application is perceived to be, the more likely it is to be used regularly ^1,2 .

Why not everyone prefers solid dosage forms

Several studies show that a significant proportion of the adult population reports difficulty swallowing tablets or capsules. ^{^3,4} These so-called "difficulties swallowing" do not only affect older people but can also occur in healthy adults. Therefore, choosing an alternative dosage form may be more practical for some people—regardless of the nutrient it contains.

What is a mouth spray?

An oral spray is a liquid oral dosage form. It is applied using a pump mechanism that delivers a defined amount of liquid into the oral cavity.

• Controllable dosage per spray
• Use without additional water
• No solid components to swallow.
• compact and mobile use

Oral sprays have been established as a dosage form for many years ⁵ .

The oral cavity – briefly explained

The oral cavity is lined with a well-vascularized mucous membrane. ^⁶ It has been investigated in pharmaceutical research for decades as a potential site of application.^⁷ However, how nutrients are processed in the body always depends on several factors – such as their chemical structure or individual differences. Therefore, general statements about absorption rate or bioavailability are not possible.

Why HereFor uses mouth sprays

Our decision to use mouth sprays is based on practical considerations:

• easy integration into daily routines
• controllable dosage
• flexible application on the go
• modern dosage form

We make this choice for application and design reasons – not based on blanket promises of effectiveness. Routine arises from repeatability. Repeatability arises from simplicity.

Sources

1. Osterberg L, Blaschke T. Adherence to medication. New England Journal of Medicine. 2005;353:487–497.
2. World Health Organization. Adherence to Long-Term Therapies: Evidence for Action. WHO report. 2003.
3. Fields J et al. Prevalence and correlates of difficulty swallowing pills in adults. Patient preference and adherence. 2015;9:1501–1508.
4. Harnett JE et al. Adult patients with difficulty swallowing oral dosage forms: A systematic review. 2023.
5. Boateng JS et al. Buccal drug delivery systems: A review. International Journal of Pharmaceutics. 2008;353(1-2):1–12.
6. Squier CA, Kremer MJ. Biology of oral mucosa. Journal of the National Cancer Institute Monographs. 2001;29:7–15.
7. Shojaei AH. Buccal mucosa as a route for systemic delivery. Journal of Pharmaceutical Sciences. 1998;1(1):15–30.